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Alli Barnes
May 286 min read

Managing Spine Health: Understanding the Risks of NSAIDs

Managing Spine Health: Understanding the Risks of NSAIDs

We see a great deal of our patients managing their spine pain with Non-steroidal anti-inflammatory drugs (NSAIDs), including common over-the-counter options like aspirin and ibuprofen, are widely used for managing pain and inflammation. This can be helpful short-term, however, their frequent and prolonged use can lead to significant health issues, including a common one we are seeing lately- peptic ulcers. Peptic ulcers cause a host of challenges and additional pain, which indirectly impact spine health by influencing overall well-being and pain management strategies. At Reactivate Your Spine, we focus on teaching our patients total body and mind health, helping avoid the need for NSAIDs…and their potential side effects! All short-term ‘fixes’ such as a pain-reliever drug needs to be combined with lifestyle and wellness changes to help eliminate the pain, or the chronic pain-reliever use can be destructive to the whole body. 


The Risk of Overuse

NSAIDs work by blocking enzymes involved in inflammation, notably COX-1 and COX-2. While effective at reducing pain, this inhibition can compromise the gastrointestinal tract's protective lining, making it susceptible to ulcers. The symptoms of peptic ulcers—severe stomach pain, bloating, and indigestion—can severely affect an individual's quality of life and ability to maintain an active lifestyle, which is crucial for spinal health. Overuse of non-steroidal anti-inflammatory drugs (NSAIDs) can lead to a variety of additional negative consequences and adverse events, affecting multiple organ systems. Here’s a quick breakdown of potential issues so you can see if your NSAID use may be related to your additional symptoms:


Gastrointestinal (GI) Effects

  • Peptic Ulcers: As already mentioned, NSAIDs can cause peptic ulcers by damaging the stomach’s protective lining.

  • Gastrointestinal Bleeding: This is one of the most common serious adverse effects, which can sometimes be life-threatening.

  • Gastritis: Inflammation of the stomach lining, often presenting with pain and sometimes bleeding.


Cardiovascular Risks

  • Increased Blood Pressure: NSAIDs can lead to elevated blood pressure, potentially exacerbating hypertension.

  • Heart Attack and Stroke: Some NSAIDs, especially when used in high doses or for long periods, have been associated with an increased risk of heart attack and stroke.


Kidney Damage

  • Acute Kidney Injury: NSAIDs can reduce blood flow to the kidneys, which can lead to kidney damage, especially in those already at risk.

  • Chronic Kidney Disease: Prolonged use can lead to a decline in kidney function over time.


Hepatic Effects

  • Liver Damage: Although less common, some individuals may experience liver damage from prolonged NSAID use, typically reversible upon discontinuation of the drug.


Other Effects

  • Asthma Exacerbation: In susceptible individuals, NSAIDs can trigger bronchospasm and exacerbate asthma symptoms.

  • Allergic Reactions: Rashes, angioedema, and other allergic reactions can occur, sometimes necessitating immediate medical attention.

  • Increased Risk of Infection: Recent studies suggest that regular use of certain NSAIDs may impair the immune system's ability to fight off infections, particularly bacterial ones.


Drug Interactions

  • Anticoagulants: NSAIDs can increase the risk of bleeding when taken with drugs like warfarin.

  • ACE Inhibitors and Diuretics: When used with NSAIDs, these medications' effectiveness can be reduced, and the risk of kidney problems increases.


Special Populations

  • Elderly: Older adults are more susceptible to the adverse effects of NSAIDs, including gastrointestinal and renal effects.

  • Pregnant Women: NSAIDs, especially in the third trimester, are linked to risks such as premature closure of the fetal ductus arteriosus and oligohydramnios (low amniotic fluid).


For anyone regularly using NSAIDs, particularly at high doses or over extended periods, it's crucial to manage usage carefully and consult functional healthcare professionals for safer alternatives and necessary adjustments in therapy. This is especially important for those with pre-existing conditions that could be exacerbated by NSAID use.



Lifestyle and Dietary Adjustments

To minimize the risk of NSAID-induced ulcers while managing spine-related pain, consider integrating the following strategies into your daily routine:

  • Increase Mucilage-Rich Foods: Foods like slippery elm and marshmallow root provide a soothing mucilage that coats the stomach lining, offering a protective barrier against irritants.

  • Probiotic Foods: Incorporate foods like kefir and yogurt into your diet. Probiotics help maintain a healthy gut flora balance, which can be disrupted by NSAIDs.

  • Antioxidant-Rich Foods: Consuming a diet rich in fruits and vegetables can boost your body's natural defenses, helping to repair and protect the gastric lining.

  • Adequate Hydration: Drink a water upon waking and stay upright. Drinking real cranberry juice, known for its ability to block harmful bacteria like H. pylori from adhering to the stomach lining, can offer protective benefits.


Alternative Pain Management

For those managing chronic spine pain, finding alternatives to NSAIDs can reduce the risk of gastrointestinal issues. We can help you based upon your specific needs and goals. Here are a few things that may be useful:

  • Physical Therapy: Engaging in tailored physical therapy can alleviate spinal pain without the side effects of NSAIDs.

  • Heat/Cold Therapy: Apply heat or cold packs to affected areas to reduce inflammation and pain.

  • Acupuncture: This traditional technique can help manage pain and reduce the need for painkillers.

  • Red Light Therapy: Using low-level wavelengths of red light can penetrate deep into the body to reduce inflammation and promote healing. This therapy is gaining popularity for its ability to alleviate chronic pain, including back pain, without invasive procedures.

  • Stretching: Regular stretching can improve flexibility, reduce stiffness, and decrease pain in the spine. Stretching exercises specifically designed for the back can help maintain spinal health and prevent pain flare-ups.

  • Massage: Therapeutic massage can help relieve muscle tension in the back, improve circulation, and increase range of motion. Regular massage sessions can be particularly beneficial for chronic pain management.

  • Yoga: Practicing yoga involves stretches and poses that enhance flexibility, strength, and balance. Yoga can also help reduce stress levels, which is often a contributing factor in chronic pain conditions.

  • Meditation: Meditation can help manage pain by reducing stress and enhancing your perception of well-being. Regular meditation may alter pain pathways and provide a psychological buffer against daily stresses that can exacerbate spine pain.

  • Core Correction: Strengthening the core muscles through targeted exercises can support the spine, reduce the load on the back, and decrease pain. A strong core is crucial for maintaining proper posture and preventing injuries. Join our next in-person Core Corrector Class, or our on-line class which is available to all of our Spine Concierge Patients for free!

  • Breathwork: Techniques focusing on controlled breathing can not only improve oxygen circulation but also reduce tension and pain perception. Breathwork can be a powerful tool for managing stress and pain simultaneously.


Herbal Remedies and Supplements

In addition to lifestyle and dietary changes, certain herbal remedies and supplements can support gastrointestinal and spine health:

  • Slippery Elm: For GI protection- Known for its soothing properties on the mucous membranes.

  • Marshmallow Root: For GI protection: Helps coat and soothe the gastrointestinal tract.

  • Turmeric (Curcumin): Curcumin, the active ingredient in turmeric, is renowned for its potent anti-inflammatory properties. It can help reduce inflammation associated with spinal pain and is also beneficial for overall joint health.

  • Ginger: Another powerful anti-inflammatory herb, ginger can help reduce pain and swelling in the spine similar to NSAIDs, but with fewer side effects.

  • Boswellia: Often used in traditional medicines, Boswellia has been found effective in reducing inflammation and pain, making it a valuable supplement for those suffering from chronic back and spinal issues.

  • Omega-3 Fatty Acids: Found in fish oil and flaxseed, omega-3s are excellent for reducing inflammation throughout the body, including the spine.

  • White Willow Bark: Known as nature’s aspirin, white willow bark contains salicin which the body converts into salicylic acid, providing pain relief and anti-inflammatory benefits similar to aspirin but without the harsh gastrointestinal effects.

  • Devil’s Claw: Used for centuries in Africa, this herb has shown promise in treating pain and inflammation, particularly in the lower back.


Incorporating these herbs and supplements into your regimen can help manage spine-related pain and inflammation while also supporting your gastrointestinal health. As with any supplement, or herb,  it's very important to consult with us or another qualified nutrition-savvy healthcare professional before starting, especially if you have existing health conditions or are taking other medications.



Conclusion

While NSAIDs are effective for short-term pain relief, their overuse can lead to significant health complications, including peptic ulcers, which can impact overall health and spine condition. By adopting a holistic approach involving dietary changes, alternative pain management techniques, and supportive supplements, you can protect their gastrointestinal health while effectively managing spine-related pain. We are happy to help you achieve you Spine and overall health goals at Reactivate Your Spine. 



References


The research and information provided in this blog is for educational purposes only and is not intended to diagnose or treat any condition. This content should not be used as a substitute for meeting with us, or your medical professional for medical advice, diagnosis, or treatment. Always consult with your doctor or another qualified health provider with any questions you may have regarding a medical condition or health concerns.


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